NEET · BiologyHard
A patient with chronic obstructive pulmonary disease shows a shift in the oxygen-hemoglobin dissociation curve to the right. Which of the following physiological conditions most likely contributes to this shift?
- A.Decreased partial pressure of carbon dioxide
- B.2,3-BPG
- C.Increased blood pH
- D.Decreased body temperature
Show correct answer & step-by-step solution
Correct answer: B — 2,3-BPG
Solution
- A rightward shift in the oxygen-hemoglobin dissociation curve indicates decreased affinity of hemoglobin for oxygen.
- Factors promoting this shift include increased , decreased pH, increased temperature, and increased .
- Among the options, increased is a known metabolic adaptation to chronic hypoxia.
- Hence the answer is (B).
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