NEET · BiologyHard
Which of the following statements accurately describes the role of the complement system in the innate immune response against bacterial pathogens?
- A.The classical pathway is initiated by the binding of to the surface of the pathogen directly
- B.The membrane attack complex is formed by the sequential assembly of , , , , and multiple molecules
- C. and act as potent opsonins to facilitate phagocytosis by macrophages
- D.The alternative pathway requires the presence of specific antibodies for activation
Show correct answer & step-by-step solution
Correct answer: B — The membrane attack complex is formed by the sequential assembly of , , , , and multiple molecules
Solution
- The complement cascade culminates in the formation of the membrane attack complex ().
- The assembly begins with the cleavage of into and .
- recruits , , and to the membrane, followed by the polymerization of multiple molecules.
- Hence the answer is (B).
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