JEE Main · ChemistryMedium
The denaturation of proteins leads to which of the following changes?
- A.Breaking of peptide bonds in the primary structure.
- B.Loss of biological activity due to disruption of secondary and tertiary structures.
- C.Conversion of globular proteins into fibrous proteins without loss of function.
- D.Increase in the solubility of the protein in water.
Show correct answer & step-by-step solution
Correct answer: B — Loss of biological activity due to disruption of secondary and tertiary structures.
Solution
- Proteins maintain their biological activity through specific 3D conformations.
- Denaturation involves the disruption of hydrogen bonds, ionic interactions, and hydrophobic interactions.
- These interactions maintain the secondary and tertiary structures of the protein.
- The primary structure, defined by peptide bonds, remains intact during denaturation.
- Hence the answer is (B).
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