NEET · BiologyHard

Which of the following physiological changes would occur if the juxtaglomerular apparatus cells were damaged, preventing the release of renin?

  1. A.Increased systemic blood pressure due to compensatory vasopressin release
  2. B.Decreased aldosterone secretion leading to hyponatremia and hyperkalemia
  3. C.Increased glomerular filtration rate due to afferent arteriole dilation
  4. D.Enhanced sodium reabsorption in the distal convoluted tubule
Show correct answer & step-by-step solution

Correct answer: BDecreased aldosterone secretion leading to hyponatremia and hyperkalemia

Solution

  1. Renin converts angiotensinogen to angiotensin I.
  2. Angiotensin II stimulates the adrenal cortex to release aldosterone.
  3. Aldosterone promotes sodium reabsorption and potassium excretion in the distal tubule.
  4. Lack of renin leads to low aldosterone, causing sodium loss and potassium retention.
  5. Hence the answer is (B).

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