NEET · BiologyMedium
Which enzyme is responsible for the decarboxylation of pyruvate to form acetyl-CoA in the mitochondrial matrix?
- A.Pyruvate dehydrogenase complex
- B.Pyruvate carboxylase
- C.Pyruvate kinase
- D.Citrate synthase
Show correct answer & step-by-step solution
Correct answer: A — Pyruvate dehydrogenase complex
Solution
- Pyruvate undergoes oxidative decarboxylation in the mitochondrial matrix.
- The reaction is .
- This complex requires cofactors like , , and .
- Hence the answer is (A).
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