NEET · BiologyHard
During the absolute refractory period of a neuron, which of the following states of the voltage-gated sodium channels prevents the generation of a second action potential?
- A.The activation gate is closed and the inactivation gate is open
- B.Both the activation and inactivation gates are closed
- C.The inactivation gate is closed and the activation gate is open
- D.Both the activation and inactivation gates are open
Show correct answer & step-by-step solution
Correct answer: C — The inactivation gate is closed and the activation gate is open
Solution
- During depolarization, the activation gate opens.
- At the peak of the action potential, the inactivation gate closes.
- The channel remains in this inactivated state until the membrane repolarizes.
- While the inactivation gate is closed, no stimulus can open the channel.
- Hence the answer is (C).
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