NEET · BiologyHard

During the repolarization phase of an action potential, the rapid efflux of potassium ions is primarily driven by which of the following mechanisms?

  1. A.Activation of voltage-gated channels and the electrochemical gradient
  2. B.Inactivation of voltage-gated channels and active transport via pump
  3. C.Opening of ligand-gated chloride channels causing hyperpolarization
  4. D.Closure of voltage-gated channels and passive diffusion of ions
Show correct answer & step-by-step solution

Correct answer: AActivation of voltage-gated channels and the electrochemical gradient

Solution

  1. At the peak of the action potential, voltage-gated channels inactivate.
  2. Voltage-gated channels open in response to depolarization.
  3. The electrochemical gradient favors the efflux of ions from the intracellular space.
  4. This efflux restores the negative resting membrane potential.
  5. Hence the answer is (A).

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